Priceless Floyd Mayweather reaction to TRT question (Video). He may be "Money" inside the boxing ring, but the pound-for-pound king is clueless when it comes to testosterone replacement therapy (TRT), which continues to plague the world of mixed martial arts (MMA). His reaction is somewhat surprising, considering how often he's suggested rival pugilist Manny Pacquiao is enhancing his performances. Speaking of which, you can see results, videos and reactions of Mayweather's win over Miguel Cotto last Saturday night in Las Vegas right here.