Pacquiao vs. Rios odds: 'Pac Man' opens as 3-to-1 favorite over 'Bam Bam' for Macao boxing bout

Jeff Gross

This could be the biggest fight of Manny Pacquiao's career. A win puts him right back in the pound-for-pound discussion while a loss would likely send him tumbling down the rankings, perhaps for good.

Longtime boxing superstar and former pound-for-pound great Manny Pacquiao will return to the squared circle later this year when he takes on Brandon Rios in a 12-round welterweight showdown at the Venetian Macao Resort Hotel in Macao, China, on Nov. 23, 2013.

And he'll do it at -400, according to Bovada.lv.

Pacquiao (54-5-2) opened as a 3-to-1 favorite over Rios (+300) despite the Filipino's recent struggles. After suffering a controversial split decision loss to Timothy Bradley last June in Las Vegas, Nevada, "Pac Man" was knocked out cold by Juan Manuel Marquez in December.

See it again here.

Rios (31-1-1), recently suffered the first defeat of his career by way of unanimous decision in a rematch against Mike Alvarado last March at the Mandalay Bay Events Center in "Sin City." The 27 year-old "Bam Bam" has 23 wins by way of knockout, but has not yet faced the quality of opposition that Pacquiao has.

Nothing like moving straight to the head of the class.

While it's still early, let's get some feedback on these numbers. About what you would expect? And how much do you think they will change by fight night?

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