File this one under "Extremely Interesting."

Ultimate Fighting Championship (UFC) President Dana White recently took to Twitter to confirm that the UFC 146 co-main event between Frank Mir vs. Cain Velasquez, which was billed as a number one Heavyweight contender eliminator match, will remain untouched.

Under normal circumstances, it wouldn't be newsworthy information whatsoever. But, thanks to Alistair Overeem and his unnatural testosterone levels, these are remarkably abnormal circumstances.

"The Reem" was supposed to challenge UFC Heavyweight Champion Junior dos Santos; however, his "surprise" test results have cast a long shadow over the likelihood of the colossal clash making the Memorial Day weekend marquee.

Let's be clear: Overeem, for now, still has the opportunity to plead his case to the Nevada State Athletic Commission (NSAC), but has yet to request for his "B" sample to be tested to confirm (or deny) the positive result. He'll likely need a more positive/contradictory finding, as well as have an airtight explanation for his elevated testosterone levels, to be granted a license to fight in "Sin City."

That's a long shot

And even if he is successful, the world's leading mixed martial arts (MMA) promotion probably requires a faster resolution to market the all-heavyweight pay-per-view (PPV) main card that will emanate from the MGM Grand Garden Arena in Las Vegas, Nevada, on May 26, 2012.

Mir, who volunteered himself to replace Overeem should he be scratched from the card, appeared to be the front-runner to replace the K-1 champion. However, White's latest remarks, if indeed true, take the former champion out of replacement running.

So if not Mir or Velasquez, then who? We know that Dan Henderson is willing to accept the fight, but he's a very small Light Heavyweight at best. And could Mark Hunt seriously be under consideration? The plot thickens.

Stay tuned to MMAmania.com for ongoing updates to Overeem's questionable status for the upcoming UFC 146 event, as well his possible "mystery" replacement as they become available. In the meantime, be sure to check out or complete UFC 146 archive right here.