"Cigano" and Velasquez aren't exactly strangers, having faced off once before at the inaugural UFC on Fox 1 event last year, with dos Santos getting the best of the former Ultimate Fighting Championship (UFC) heavyweight champion, knocking him out in the very first round.
"The Reem," however, believes their rematch will have a drastically different result.
Overeem and "JDS" were set to tango at UFC 146 earlier this year, but the former dual K-1 / Strikeforce champion's extremely high testosterone levels and subsequent suspension levied down by the Nevada State Athletic Commission (NSAC), canceled the much-anticipated showdown.
"Cigano," instead, went on to defeat Frank Mir at the Memorial Day weekend event, while Velasquez absolutely destroyed Antonio Silva in the night's co-main event to secure his rematch against the Brazilian striker, which is set to go down at UFC 155 on Dec. 29, 2012 in Las Vegas, Nevada.
Though Overeem would love nothing more than to get his hands on dos Santos, the Dutch striker believes Velasquez will take care of business for him in "Sin City" via ground-and-pound.
His word to The Las Vegas Sun:
"I want dos Santos to win so I can beat him, but I think Cain is going to take care of him for me, unfortunately. Junior is going to get taken down. He's going to get ground-and-pounded. (Junior's) been doing the zig-zag. He wants to fight me then he doesn't, so then he fights Cain. I think he's going to have his hands full with Cain. He's going to lose."
Many, Overeem included, feel Velasquez's best chance against "Cigano" will be if he utilizes his outstanding wrestling skills. Something "Brown Pride" looked to enforce in their original encounter. Unfortunately for the NCAA Division-1 wrestling standout, dos Santos didn't give him the chance to get any offense going, ending his title reign in a little more than one minute of the opening round.
Meanwhile, Overeem has his hands full against another Brazilian as he takes on the aforementioned Antonio Silva at UFC 156 on Feb. 2, 2013, in Las Vegas. A win over "Bigfoot" will likely earn him a title shot against the winner of UFC 155's heavyweight title fight.
In Overeem's perfect world, the former K-1 champion would have his chance to swing leather against dos Santos, however, his money is on Velasquez to reclaim the title.
Anyone (dis) agree?